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Objective: To assess heart rate variability (HRV) by the results of 24-hours ESG monitoring in patients with infection endocarditis (IE) before surgery and over a 6-month period after the surgical correction of valve heart pathology. Material and Method: In 35 patients included into the study, an assessment of initial HRV (before surgery, I test) was performed by the results of 24-hours EÐiG monitoring on the 11,0±1,0 day after the surgery; in 3 and 6 months after the surgery. Results: More than a half of IE patients in pre-and early postoperative periods (56% and 57% respectively) were found to have hypersympaticotonia which was associated with the reduction of cardiac rhythm variability temporary indices (standard deviation NN intervals – SDNN, standard deviation average NN intervals – SDANN- i). In early postoperative period acute reduction of HRV was revealed in patients with severe complications, such as myocarditis, valvular abscesses, severe heart failure associated with cardiac valve destruction as well as the perioperation myocardial infarction. In 3 and 6 months after the IE surgical treatment the number of patients with significant HRV reduction decreased. The significant hypersympaticotonia maintained in patients with previous MI and myocarditis that led to the development of heart failure with the reduction of global left ventricle (LV) contractility. The evidence of significant hypersympaticotonia in patients with type II diabetes mellitus was subject to diabetic neuropathy progressing underlying secondary immune failure in the settings of IE. Conclusion: The low level of HRV can be used as a complication marker in IE patients including the post-operative period.

The significance of cardiac rhythm variability value assessment in partients with infective endocarditis