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Background: we aimed to evaluate the features of lung nodules and masses in Ct scan that help to distinguish malignant lesions from benign ones.  Method: The study was performed on 50 pulmonary lesions biopsied at the Shahid Faghih Hospital by an interventional radiologist. CT scan findings were evaluated by a radiologist and compared with pathologic outcomes. Data was entered into SPSS software and by Descriptive statistical methods of frequency and Roc curve analysis and Chi-squared test and T-test at the level of alpha 0.05 was analyzed.  Results: The relationship between smoking and malignancy was determined in this study. There was no significance found in mean age and sex, lesion density and enhancement of benign and malignant nodules. Smooth border was mostly seen in benign lesions and lobulated and spiculated borders in malignant lesions. Popcorn calcification was in favor of benignity and calcification in periphery of lesion was in favor of malignancy. Cavity was mostly seen in benign lesions  Conclusion: smoking and the spiculated or lobulated margins, calcification in the periphery of the lesion were associated with malignant lesions, and the smooth margin and popcorn calcification and cavity formation were mostly seen in benign lesions. Enhancement showed no significance.

Correlation of CT-scan findings of lung lesions and pathologic diagnosis