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1.1. Purpose: This case report was designed to investigate the visual, retinal, and macular pigment density (MPOD) changes in a diverse group of subjects being treated in a clinical setting with a supplement designed to increase macular pigment density, with follow-up at 6 month intervals over a 24 month time period   1.2. Methods:A pre-screening intake history was recorded to allow identification and selection of the patient population to be followed, baseline examination of the central retina, macular pigment optical density (MPOD), visual function testing, and SD-OCT imaging of the macular region were performed, and follow-up visits were performed at 6,12,18, and 24 months.   1.3. Results. Improvements were recorded in macular pigment density and visual functions, with improvement in macular appearance and changes in metamorphopsia.   1.4. Conclusion: Adding lutein/zeaxanthin/fish oil/antioxidant macular supplement with zinc, along with advice of sun protection, dietary changes and smoking recommendations improved visual functioning, and exhibited positive retinal changes documented by SD-OCT and fundus photography.

Case Report of Dietary Supplements Improving Macular Pigment and Visual Function