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Twelve adult dogs fasted over night were used under Nembutal anesthesia. The intragastric pressure was measured by strain-gauge method with open tip cannula via duodenum. The stomach was filled through the cannula with 50 ml of Ringer's solution in a stepwise manner every two minutes until a total of 600 ml. Following results were obtained: 1) The intragastric pressure was more elevated on the vagotomized and the splanchnicotomized dogs than on the intact animals by a stepwise augmentation of Ringer's solution. 2) On the animals which were transected totally the extrinsic nerves, the increase of the intragastric pressure was the most. 3) It may be concluded that the elevation of intragastric pressure after denervation of the extrinsic nerves, due to the abolitions of vagal and splanchnic inhibitory reflexes.

THE INFLUENCE OF TRANSECTION OF EXTRINSIC NERVES TO STOMACH ON THE FLUCTUATION OF INTRAGASTRIC PRESSURE IN DOG