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Reactive hypoglycaemia after gastric bypass surgery is characterized primarily by excessive postprandial hyperinsulinaemia and resultant neuroglycopaenic symptoms. The elusive pathophysiology of this problem has made treatment challenging. We describe the first case report where treatment with the Sodium Glucose Transporter Inhibitor canagliflozin has reduced hypoglycaemic episodes after failure of other therapies.

Successful use of canagliflozin for treatment of post-bariatric surgery hypoglycaemia unresponsive to other therapy