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REFERENCE 1. Leporati P, Landek-Salgado MA, Lupi I, Chiovato L, Caturegli P. IgG4-related hypophysitis: a new addition to the hypophysitis spectrum. J Clin Endocrinol Metab. The Endocrine Society; 2011 Jul;96(7):1971–80. 2. Bando H, Iguchi G, Fukuoka H, Taniguchi M, Yamamoto M, Matsumoto R, et al. The prevalence of IgG4-related hypophysitis in 170 consecutive patients with hypopituitarism and/or central diabetes insipidus and review of the literature. Eur J Endocrinol. European Society of Endocrinology; 2014 Feb 1;170(2):161–72. 3. SHIMATSU A, OKI Y, FUJISAWA I, SANO T. Pituitary and Stalk Lesions (Infundibulohypophysitis) Associated with Immunoglobulin G4-related Systemic Disease: an Emerging Clinical Entity. Endocr J. The Japan Endocrine Society; 2009;56(9):1033– 41. 4. Byrne TN, Stone JH, Pillai SS, Rapalino O, Deshpande V. Case 31-2016. Cabot RC, Rosenberg ES, Harris NL, Shepard J-AO, Cort AM, Ebeling SH, et al., editors. N Engl J Med. Massachusetts Medical Society; 2016 Oct 13;375(15):1469–80. 5. Hattori Y, Tahara S, Ishii Y, Kitamura T, Inomoto C, Osamura RY, et al. A Case of IgG4-Related Hypophysitis Without Pituitary Insufficiency. J Clin Endocrinol Metab. Oxford University Press; 2013 May 1;98(5):1808–11. CONCLUSION AND LEARNING POINTS While acute hypophysitis presenting with florid symptoms or ophthalmological involvement may require high dose steroid, this case presented as indolent “burn-out” disease was safely managed with mere hormonal replacement with no evident progression in the 3 year of follow-up.

Case report: Indolent IgG4 hypophysitis with partial anterior pituitary failure