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During pregnancy, the thyroid volume (TV) increases by 20% to 35% in areas with iodine deficiency. In iodine-sufficient countries, while some studies showed an increase in TV by 10-15%, others did not observe any change in TV during pregnancy. Thyroid nodules may be present in up to 15-35% of pregnant women in areas with moderate iodine deficiency. However, in areas with iodine-sufficient, thyroid nodules were investigated in a few number of studies

The effects of iodoprophylaxis on thyroid volume and nodular size during pregnancy in an iodine-sufficient area