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Role of sex hormones in the pathogenesis and development of thyroid tumors: thyroid cancer are about 2,7 fold times more frequently diagnosed in the reproductive age women compared to similar aged men (Davies et al, 2006); recent pregnancy associated with a doubling in thyroid cancer risk (Rossing et al, 2000). ERα and ERβ have opposite actions on cell survival and proliferation: Era= proliferative and antiapoptotic effect; Erb= differentiative and pro-apoptotic effect Aim of the study was to analyse estrogen and progesterone receptors expression in differentiated thyroid cancer and to correlate it with clinical and molecular features (BRAFV600E) PATIENTS (n=190)

endocrine abstracts

The evaluation of sex hormone receptors in papillary thyroid cancer as an additional tool in the post-operative risk stratification and in the pre-gravidic counselling of women with persistent disease