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• A correlation of T, A (r=0.41, P<0.001) and fTc (r=0.45, P<0.001) with DEQ levels was significant. • DEQ levels were significantly higher in women with PCOS compared to controls (P<0.05). • Increased levels (95percentile of serum levels in control women) of T, fTc, A and DEQ were noted in 73%, 71%, 69% and 82% in women with PCOS, respectively. • A total of 98% of the subjects with the highest quartile of DEQ levels had PCOS. • The optimal DEQ cutoff value for predicting PCOS was 151.9 pg/L and the area under the ROC curve was 0.97. • The DEQ levels were correlated with ovarian volume and ovarian follicle number, total cholesterol, LDL cholesterol, fasting plasma insulin, post-load 2-h plasma insulin.

Serum dihydrotestosterone equivalent levels in women: a new index of hyperandrogenemia