English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

A thyroid nodule discovered in a patient with Graves`disease(GD) should be evaluated and managed according to guidelines .A subcentimeter incidental thyroid cancer founded in a patients with GD,without high-risk history,without suspicious sonographic(US) features has not been reported yet. A 40 year –old female patient,presented to our hospital with symptoms of thyrotoxicosis.On physical examination heart rate was 120 bpm, blood pressure of 130/90mmHg ,with a nontender thyroid gland,with murmurs on auscultation ,without nodules on palpation.No exophtalmos or skin changes were noted .The patient was under treatment with Methimazole 5mg twice daily and beta blocker,since seven months.Labaratory Investigations showed AST:93I/l,ALT:156U/l(N:<40U/m).Thyroid function tests revealed freeT3:22.52pg/ml(N:24.4),freeT4:63.04ng/dl(N:10.6-19.4) and TSH:0.003uUI/ml(N:0.35-4.94).TRAbs:1.8 UI/ml(N<1).A thyroid ultrasound detected a diffuse enlargement with diffuse hypervascularity of thyroid,with a hyperechoic rounded nodule measuring 9m÷6.4mm in the left lobe(with regular borders,with halo,without microcalcifications) and a hypoechoic right lobe.A scintigraphy showed a increased diffuse uptake,suggestive of GD.Fine needle aspiration biopsy(FNAB) was not performed. Our patient underwent a total thyroidectomy after two months,in a euthyroid state.Histopatological examination of the thyroid gland showed a focus of papillary microcarcinoma,follicular variant, lying into the nodule detected on US.

Incidental thyroid cancer in a subcentimetric nodule with benign ultrasound criteria in a patient with Graves' disease