Renal loss of leptin in patients with nephrotic syndrome
Author(s) -
Michael Schroth,
Michael Gröschl,
H. G. Dörr,
WF Blum,
Wolfgang Rascher,
Jörg Dötsch
Publication year - 2001
Publication title -
european journal of endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.897
H-Index - 148
eISSN - 1479-683X
pISSN - 0804-4643
DOI - 10.1530/eje.0.1450463
Subject(s) - leptin , medicine , proteinuria , endocrinology , creatinine , urine , excretion , nephrotic syndrome , radioimmunoassay , urinary system , obesity , kidney
In humans, short term changes of serum leptin lead to alterations in food intake and energy expenditure. The objective of the present study was to relate urine leptin concentrations with the extent of proteinuria in patients with nephrotic syndrome (NS). A second goal was to investigate the impact of potential urinary leptin losses on serum leptin concentrations and body composition.
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