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― Heavy metal storage and essential elements deficiency are two important issues in dialysis patients. Geographic region and dietary habits might affect essential trace elements concentration in body. Trace elements (TEs) status has not been studied previously in dialyzed patients in Ahvaz city. The aim of this study is to compare blood concentrations of six TEs between dialysis patients and normal group in Ahvaz, the center of Khuzestan province, in southwest of Iran. Material and Methods ― We studied 33 end-stage renal disease (ESRD) patients and 33 normal cases. TEs assayed in serum samples, except lead, which assessed in whole blood. We used atomic absorption spectroscopy in this pressure. We used ANOVA and Tukey-HSD statistical analysis as well as binary logistic regression for calculating Odds ratio. Results ― There was a significant difference between case and control groups for magnesium (Mg), aluminium (Al) and lead (Pb) (P<0.05), but there was not a significant difference for copper (Cu) and selenium (Se) (P>0.05). Zinc (Zn) level change was not significant. Al and Pb level increased after dialysis but Mg level decreased. All calculated Odds ratios were weak for all investigated trace elements. Different results published about TEs level in ESRD patients. Increase in TEs level in case group may be as a result of chronic poisoning through dialysis and after dialysis hemoconcentration, respectively. In order to understand the exact reason of this observation we need comprehensive and monitored studies. TEs disturbances in Ahvaz ESRD patients imply the importance of periodically studies. Conclusion ― The most important interpretations and suggestions of this study is that the TEs level is different among different population. Then, Iranian health-providers should consider to TEs assessment in both healthy and patient cases. Periodical measurement of TEs is essential for ESRD patients and it can be helpful in preventing TEs deleterious effects.

russian open medical journal

Comparison of zinc, copper, selenium, magnesium, aluminium and lead blood concentrations in end-stage renal disease patients and healthy volunteers in Ahvaz, southwest of Iran