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Background: Bone substitutes, such as allografts, xenografts, and alloplasts, have been proposed in several augmentation procedures. Purpose: The aim of the present study was to evaluate radiographically and histologically the pre-hydrated collagenated cortico-cancellous granules in maxillary sinus augmentation. Materials and Methods: This study conducted on eight sinuses with residual bone height less than five mm using lateral approach technique specimens, retrieved after 6 months from augmented sinuses. The specimens processed to be observed under light microscopy. Radiographic measurements presented as means one standard deviation of bone height in millimeter and density of the newly formed bone in Hu. Results: Most of the particles were surrounded by newly formed bone with large osteocyte lacunae. Some slides showed marrow spaces and residual graft material reveals the beginning of new bone formation. Conclusion: The present results show that pre-hydrated collagenated cortico-cancellous granules is a biocompatible, osteo-conductive biomaterial that can be used for maxillary sinus augmentation procedures without interfering with the normal reparative bone processes.

Evaluation of Pre-hydrated Collagenated Cortico- Cancellous Granules (Mp3®) in Augmentation of the Maxillary Sinus (Preliminary Study)