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hronic kidney disease (CKD) is a syndrome characterized by impaired renal metabolism, which occurs dynamically and progressively, culminating in the loss of physiological functions of the kidneys. In this study, 7 felines, regardless of breed and sex, aged between 4 and 13 years, affected by stage 2 CKD, were treated with multipotent adult progenitor cells of feline adipose tissue (MAPCs-FAT) from a healthy donor animal. Three infusions were performed through the intravenous route, with an average interval of 30 days. The animals showed a significant improvement in renal function after MAPCs-FAT infusions without apparent adverse effects, clinical improvement, gain in appetite and increased disposal of animals, right after the first application. It is concluded that the therapy with MAPCs-FAT significantly contributed to the improvement of the quality of life of felines affected by chronic kidney disease stage 2.

CÉLULAS PROGENITORAS ADULTAS MULTIPOTENTES ALOGÊNICAS NO TRATAMENTO DE DOENÇA RENAL EM FELINOS