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A marine soft coral species of the genus Heteroxenia collected from Mindoro Island, Philippines yielded two cadinene sesquiterpenes, (+)-α-m uurolene (1) and a novel derivative (+)- 6 -hydroxy-α-muurolene (2 ), as well as the biologically active polyhydroxysterol, sarcoaldosterol A (3). The structure of the novel compound was unambiguously established on the basis of NMR spectroscopic ( 1 H,  13 C, COSY,  1 H-detected direct and long range  13 C - 1 H correlations) and mass spectrometric (EIMS) data. All compounds were active against the phytopathogenic fungus Cladosporium cucumerinum. The isolated terpenes were also active in the brine shrimp lethality test.

Bioactive Terpenes from the Soft Coral Heteroxenia sp. from Mindoro, Philippines