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I report on the preparation of (9-β-ᴅ-ribofuranosyl)-s-triazolo-[1,2a]-purine-6-one (2) by cycli- zation of N-1-amino guanosine (1) with formamide. The tricyclic nucleoside analogue was charac­terized by NMR-spectroscopy ( 1 H-NMR;  13 C-NMR). The utility of 2 for the introduction of “cross­links” in double stranded nucleic acids is discussed.

zeitschrift für naturforschung c

Darstellung von (9-β-ᴅ-Ribofuranosyl)-s-triazolo-[ 1,2a]-purin-6-on durch Cyclisierung von N-1-Aminoguanosin /  Preparation of (9-β-ᴅ-Ribofuranosyl)-s-triazolo-[1,2a]-purine-6-one by Cyclization of N-1-Amino Guanosine