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Colucons A ( 1 ) and B ( 2 ), new prenylated flavanones, isolated from the EtOAc-soluble sub-fraction of the whole plant of  Colutea armata  Hemsl. &amp; Lace along with four known compounds, namely, kenusanone J ( 3 ), hesperetin ( 4 ), tyrosol ( 5 ) and syringaldehyde ( 6 ), were reported for the first time from the species  armata . Their structures were elucidated by spectroscopic techniques including  1 H and  13 C NMR (distortionless enhancement by polarization transfer), and 2D NMR experiments. Compounds  1–3  showed significant antifungal activity against  Pseudallescheria boydii ,  Aspergillus niger ,  Trichophyton mentagrophytes ,  Macrophomina phaseolina  and  Candida glabrata , while compound  4  showed moderate antifungal activity.

New antifungal prenylated flavanones from Colutea armata