English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Several 2-substituted sulfanyl benzo[ d ]thiazoles were regioselectively synthesized by the reaction of benzo[ d ]thiazole-2-thiol ( 1a ) with a variety of reagents under different basic conditions. Some 2-(2,3-disubstituted propyl sulfanyl)benzo[ d ]thiazoles were obtained from 2-(allylthio)benzo[ d ]thiazole, which was prepared by the allylation of  1a  with allyl bromide in the presence of sodium hydride in dry  N , N -dimethylformamide. Reaction of  1a  with various pyrazolyl-quinoxaline derivatives was also investigated. Better yields and shorter reaction time were achieved for the synthesis of some derivatives by using ultrasound irradiation. The structural elucidation of all compounds was based on both analytical and spectroscopic data. The newly synthesized compounds were tested  in vitro  for their antitumor activity against Ehrlich ascites carcinoma (EAC) cells grown in albino mice. Doxorubicin was used as a standard antitumor antibiotic, and some compounds showed half maximal inhibitory concentration (IC 50 ) in the range 40–68 μg mL −1 .

zeitschrift für naturforschung b

Synthesis, characterization, and antitumor activity of some novel S-functionalized benzo[ d ]thiazole-2-thiol derivatives; regioselective coupling to the –SH group