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Laparoendoscopic single-site surgery (LESS) has become a novel minimally invasive approach applied as an option to perform hysterectomy. The aim of the study was to evaluate the influence of LESS hysterectomy on the sexual function in women with benign gynecologic indications. From October 2016 to May 2021, a total of 486 premenopausal, sexually active women were eligible. Female sexual function index (FSFI) was used to assess sexual function preoperatively and 6, 12 months postoperatively. Total FSFI score ≤26.55 indicated female sexual dysfunction (FSD). Compared with pre-operation, each subdomain and total FSFI scores increased at 6 (all  p  &lt; 0.05) and 12 months (all  p  &lt; 0.001). Prevalence of FSD decreased at 6 (30 vs 39.9%,  p  = 0.002) and 12 months (27 vs 39.9%,  p  &lt; 0.001). In patients with preoperative FSD, each subdomain and total FSFI scores improved at 6 and 12 months (all  p  &lt; 0.001), while decreased at 6 months ( p  &lt; 0.001) and had no significant difference at 12 months ( p  = 0.54) in patients without preoperative FSD. These results suggest that LESS hysterectomy has a significant positive effect on the sexual function in women with benign gynecologic diseases, especially those with preoperative FSD.

Variations in sexual function after laparoendoscopic single-site hysterectomy in women with benign gynecologic diseases