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To compare foot length deficits between patients with Laron syndrome (LS) (primary growth hormone [GH] insensitivity) and congenital isolated GH deficiency (IGHD) and their response to replacement therapy with insulin-like growth factor-I (IGF-I) and hGH, respectively.

journal of pediatric endocrinology and metabolism

Foot Length Before and During Insulin-like Growth Factor-I Treatment of Children with Laron Syndrome Compared to Human Growth Hormone Treatment of Children with Isolated Growth Hormone Deficiency