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Aqueous extract of Moringa oleifera leaves (MOE) is a potent inducer of endothelium-dependent relaxation of mesenteric resistance arteries of rats induced to be hypertensive using N ω -nitro-L-arginine methyl ester (L-NAME). Hydrogen sulfide (H 2 S) has been shown to participate in endothelium-dependent relaxation of small resistance arteries. Therefore, this study aimed to investigate whether endothelial H 2 S-dependent signaling plays a role in the vasorelaxation in response to MOE.

journal of complementary and integrative medicine

Hydrogen sulfide as a mediator of endothelium-dependent relaxation evoked by  Moringa oleifera  leaf extract in mesenteric arterial beds isolated from L-NAME hypertensive rats