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The present work deals with the synthesis of 2-cyano- N ′-(3-(2-(2-cyanoacetyl) hydrazinyl) cyclohex-2-en-1-ylidene) acetohydrazide  3  that used as a key precursor in the manufacture of new heterocyclic derivatives, such as pyrazole, pyrane, pyridine, and pyrole incorporating cyclohexene moiety via its reaction with a variety of nucleophilic and electrophilic reagents. The newly synthesized compounds were characterized by their elemental analyses (IR,  1 H-NMR,  13 C-NMR, and Mass spectra) and assessed for their anti-microbial activity.

Bis(2-cyanoacetohydrazide) as precursors for synthesis of novel azoles/azines and their biological evaluation