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A method for simultaneous determination of manganese, copper and zinc in scrum and packed blood cells by neutron activation analysis is described. After irradiation the samples are wet-ashed. Copper is extracted at pH 2, manganese and zinc at pH 8 with 0.05 mol/1 oxine in chloroform. Radioactive measurements are carried out with a 3" X 3" Nal (Tl) well type detector coupled to a 400 channel analyser. Results arc reported from 20 individuals.

clinical chemistry and laboratory medicine

Determination of Manganese, Copper and Zinc in Serum and Packed Blood Cells by Neutron Activation Analysis.   Studies on the metabolism of trace elements