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1. Following an intravenous injection of 250 £ adrenaline over a period of 2 min., a steep increase in the free fatty acid content of both arterial and venous blood was observed within 10 min. The arteriovenous difference, which before the injection of adrenaline is very small, increased to a maximum after 10 min., and returned to the original value after 20 min. The arterial blood was sampled from the A. bracbialis dextra, and the venous sample was obtained by inserting an approximately 20 cm long catheter deeply into the muscle tissue of the left forearm (Fig. 6). 2. Arterio-coronary-venous difference in patients suffering from cardiac insufficiency were subjected to extreme strain on a bicycle ergometer. As already reported for athletes who go in for top-strain sports (8, 9), the concentration of free fatty acids in their blood is seen to increase during the physical exertions. The concentration of free fatty acids is at its greatest after 3 min. of maximum exertion. Obviously, the arterio-coronary-venous difference during maximum exertion becomes greater as a result of an increasing extraction of free fatty acids by the heart muscle (Fig. 7). 3. The determination of free fatty acids in the plasma of horses in rest and after a training of 20 min. was made and the results are given in table 4.

Isolierung eines Xylose-haltigen Glykoproteids aus dem Erythrocyten-Stroma