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Accurate quantification of hemoglobin (Hb) A 2 is vital for diagnosing β-thalassemia carriers. This study aimed to assess the precision and diagnostic utility of HbA 2 measurements using the new high-performance liquid chromatography (HPLC) method, Premier Resolution, in comparison to capillary electrophoresis (CE).

Reliability of hemoglobin A 2 value as measured by the Premier Resolution system for screening of β-thalassemia carriers