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Background:  Fully automated chemiluminescence immunoassays (CLIAs) are emerging technologies for the detection of anti - cardiolipin (aCL) and anti-β 2  glycoprotein I (anti-β2GPI) antibodies for anti-phospholipid syndrome (APS) classification, which is commonly based on an enzyme-linked immunosorbent assay (ELISA) test result. CLIA and a homemade ELISA were used in this study to detect these antibodies, and their performances were compared.

clinical chemistry and laboratory medicine (cclm)

The clinical performance of a chemiluminescent immunoassay in detecting anti-cardiolipin and anti-β 2  glycoprotein I antibodies. A comparison with a homemade ELISA method