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The proteolytic activity of the chymotrypsin-like cationic proteins of human granulocytes is inhibited by complex formation with the acid-stable low molecular weight protease inhibitor of human bronchial mucus (Ki = 1.0 x 10(7)M). The molar combining ratio is 1:1.

The Interactions between a Low Molecular Weight Protease Inhibitor of Bronchial Mucus and Chymotrypsin-like Cationic Proteins of Granulocytes