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Activation of bovine chymotrypsinogen is catalyzed with increasing velocity by human, rabbit, boar, bull and ram acrosin. Antiboar-acrosin rabbit gamma-globulins cause a significant reduction in the proenzyme activation rate induced by boar and bull acrosin, but only a weak reduction or none if ram or rabbit acrosin is the activating agent. The antiboar-acrosin gamma-globulins from sheep strongly inhibit chymotrypsinogen activation by ram, bull and boar acrosin, and significantly inhibit the human acrosin-catalyzed reaction.

hoppe-seyler's zeitschrift für physiologische chemie

Influence of Boar Acrosin Antibodies Produced in Rabbit and Sheep on Chymotrypsinogen Activation Catalyzed by Acrosin from Boar, Bull, Ram, Rabbit and Human