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Received May 8, 1965 Introduction The Golgi apparatus in the sympathetic ganglion cells has been studied in detail by Thomas (1948). He pointed out that the Golgi apparatus in the sympathetic ganglion cells was made up of a number of discrete bodies of variable sizes, from small grains to simple spheroids. He suggested that the classical Golgi network of sympathetic neurons was due to metallic impregnation of the spheroidal system (Golgi complex) and mitochondria. How ever, our studies on the Golgi apparatus of the spinal and vagus ganglion (Tugular and nodosal) cells using the thiamine pyrophosphatase (TPPase) technique as described by Novikoff and Goldfischer (1961), showed that the Golgi apparatus takes the form of a network in some cells and a separate spheroidal system of various sizes and shapes in others (Shanthaveerappa and Bourne, 1965i). This suggests that the Golgi complex exists in both forms. The TPPase technique is not destructive to the cells and electron histo chemistry has shown that the morphology of the cell is well preserved and the Golgi complex is easily identifiable after the application of this technique. Since all the present evidence indicates that the TPPase technique is specific for the Golgi apparatus in ver tebrate cells (Baker 1963) it seems that the application of this technique to the sympathetic ganglia might help to resolve the controversy regarding the nature of the Golgi apparatus in the cells of these ganglia.

The Thiamine Pyrophosphatase Technique as an Indicator of the Morphology of the Golgi Apparatus in the Neurons