Open AccessIgG4 Related Cardiac Disease
Author(s) -
Hector Carbajal,
Lindsay Waters,
Jovan Popovich,
Milton Boniuk,
Patricia Chévez-Barrios,
Donald M. Marcus,
Sandra Lee Sessoms
Publication year - 2013
Publication title -
methodist debakey cardiovascular journal
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.552
H-Index - 23
eISSN - 1947-6094
pISSN - 1947-6108
DOI - 10.14797/mdcj-9-4-230
Subject(s) - medicine , webcast , medline , medical education , world wide web , computer science , political science , law
IgG4-related systemic disease is an inflammatory disorder that can affect many organs. This case report describes a patient who in 2004 was found to have an inflammatory pseudotumor with IgG4 pathology. Over the next 3 years, visual symptoms responded well to recurrent courses of prednisone. In 2009, the patient developed chest pain and bradycardia with subsequent third-degree heart block, necessitating placement of a pacemaker. A subsequent PET scan showed extensive involvement of multiple organs as described in IgG4 disease as well as involvement of the myocardium and SA node. Pseudotumors involving the heart have been reported but have not been shown to be related to IgG4 disease. Although there was no pathology confirmation of heart involvement, the nature and extent of the organ involvement led us to conclude that it was due to IgG4-related disease. The use of the PET scan may help identify involvement of the myocardium.