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Materials and methods. 90 patients were examined and divided into three groups: group 1 (n = 30) included patients suffering from OA grade II–III according to Kellgren and Lawrence classification with normal body mass (BMI = 21–25 kg/m2), group 2 (n = 30) – patients with NASH and OB without OA (BMI > 30 kg/m2), group 3 (n = 30) – patients with OA with NASH and OB (BMI more than 30 kg/m2). The control group consisted of 30 age-matched practically healthy persons (PHP). The average age of patients was (62.3 ± 5.7) years.

zaporožskij medicinskij žurnal

Features of the connective tissue metabolism, the content of adipokines and cytokeratin-18 in patients with non-alcoholic steatohepatitis combined with osteoarthritis and obesity