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| The study was conducted to determine the prevalence of fascioliasis in sheep in Quetta district from January to June 2007. Two hundred and fifty liver samples along with gall bladder and bile ducts were collected from sheep. Over all prevalence of liver fluke infestation in sheep was recorded as 30% in young and adult and 32% in aged sheep. Out of these positive samples Fasciola hepatica was found 50% and Fasciola gigantica 10% in case of young whereas in adults 20% with fasciola hepatica and 14%with Fasciola gigantica and in aged sheep the prevalence was recorded as 33.33% and 13.33% with fasciola hepatica and fasciola gigantica respectively. Variable degree of gross lesions were noted in affected livers included cholangitis (63.15%), biliary obstruction (57.89%), fibrosis (68.42%), hyperplasia (60%), haemorrhages (47.36%), enlargement (52.63%), fibrinous exudates (63.15%) and oedema (57.0%) in sheep during the study period. From this study it is clear that fascioliasis is a serious problem for sheep in Pakistan with highest percentage of Fasciola hepatica followed by Fasciola gigantica which causes damaging of liver with variable degrees of inflammation, haemorrhages, hyperplasia and enlargement of livers.

Study on the Prevalence and Gross Pathology of Liver Fluke Infestation in Sheep in and Around Quetta District, Pakistan