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The n-dimensional hypergeometric integrals associated with a hypersphere arrangement are formulated by the pairing of n-dimensional twisted cohomology and its dual. Under the condition of general position there are stated some results which concern an explicit representation of the standard form by a special (NBC) basis of the twisted cohomology, the variational formula of the corresponding integral in terms of special invariant 1-forms written by Cayley-Menger minor determinants. Gauss-Manin connection is also formulated and is explicitly presented in two simplest cases.

Hypergeometric integrals associated with hypersphere arrangements and Cayley-Menger determinants