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The etiology of alopecia areata (АA) still remains obscure. According to modern representations, AA is an autoimmune disease caused by a number of immune, genetic and endocrine factors. First of all, a coreceptor is distinguished that manages CD8+ (CD8 Driven) and T- cells from the regulatory factors reflecting the autoimmune nature of development of AA – Th1-type, causing T-cellular autoimmune reaction. Among methods of treatment of AA the most effective is the excimer laser with the wavelength 308nm which influences the main links of pathogenesis and has immunomodulatory effect on the area of an exposition.

Usage of immunomodulatory properties of the excimer laser 308 nm in therapy of alopecia areata