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Laboratorio de Control de Calidad de Medicamentos (LCCM), Cátedra de Química Analítica I, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, C.C. 242, S3000ZAA Santa Fe, Argentina. e-mail: yami_caro@ yahoo.com.ar; mmdezan@fbcb.unl.edu.ar Estrategia de validación aplicada a un método potenciométrico desarrollado para la determinación de fluoruro total en pastas dentales