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Current article presents commentary on official inclusion of cardiovascular prophylaxis in indications for Diabeton MR therapy. The paper features extensive review of data from ADVANCE (Action in Diabetes and Vascular Disease: PretarAx and DiamicroN Modified Release Controlled Evaluation) trial and its comparative analysis with other major randomized studies of intensive glycemic control in patients with type 2 diabetes mellitus.

Commentary on prevention of cardiovascular complications in diabetes mellitus as novel inidicationfor Diabeton MR