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A Case of Lymphoid Leukemia in a Calf with with Onset of Clinical Signs at Three Days of Age M. OKADA, K. MATSUKAWA, K. TAKAHASHI* and S. YAMASHITA* (Departments of Veterinary Pathology and* Veterinary Internal Medicine, College of Dairy Agriculture, Ebetsu, Hokkaido) SUMMARY Clinical, histopathological, and electron microsco pical observations were performed on a case of lymphoid leukemia in a calf encountered in the Chitose area in Hokkaido in 1971. This case was diagnosed as the "small lymphoid cell type" (lymphocytic lymphosarcoma) of bovine malignant lym phoma. It was also classified into the "calf multic entric type" from clinical aspects. It should be emphasized from an epidemiological point of view that the disease occurred to a three-day-old animal.