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Non-Invasive Ventilation (NIV) dates back to the iron lung. The modern era of NIV arguably began in 1995 with the demonstration of improved outcomes using NIV to treat exacerbation of Chronic Obstructive Pulmonary Disease (COPD). Subsequently NIV has become standard practice for management of acute exacerbation of COPD to decrease the need for endotracheal intubation and the problems inherent with invasive mechanical ventilation. As a practice becomes standard care, however, there is a danger of extrapolating results to groups beyond those which have been studied. In particular, there are risks of assuming that NIV will be equally effective for other causes of acute respiratory failure, and that NIV will be equally effective for all patients irrespective of the severity of illness.

Challenges of treating hypercapnic respiratory failure with non-invasive ventilation from hospital to home