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Received October 13, 2017; revised manuscript received January 18, 2018; accepted January 23, 2018; released online February 23, 2018 Time for primary review: 24 days Department of Cardiology (T.S., M. Ikezawa, A.H., S.Y., H.N., K.M.), Department of Gastroenterology (K.T.), Mie Prefectural General Medical Center, Yokkaichi; Department of Cardiology, Mie Heart Center, Meiwa (T.S.); and Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Tsu (M. Ito), Japan Mailing address: Toshiki Sawai, MD, PhD, Department of Cardiology, Mie Heart Center, 2227-1 Oyodo, Meiwa, Taki-gun, Mie 510-8561, Japan. E-mail: tsawai@clin.medic.mie-u.ac.jp ISSN-1346-9843 All rights are reserved to the Japanese Circulation Society. For permissions, please e-mail: cj@j-circ.or.jp Large Non-Bacterial Vegetation Causing Acute Aortic Regurgitation ― Unexpected Finding at Autopsy ―