Open AccessInduction Chemotherapy with FOLFIRINOX for Locally Advanced Pancreatic Cancer: A Simple Scoring System to Predict Effect and Prognosis
Author(s) -
Masayuki Tanaka,
Max Heckler,
André L. Mihaljevic,
Shigenori Ei,
Ulla Klaiber,
Ulrike Heger,
Markus W. Büchler,
Thilo Hackert
Publication year - 2022
Publication title -
annals of surgical oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.764
H-Index - 173
eISSN - 1534-4681
pISSN - 1068-9265
DOI - 10.1245/s10434-022-12569-y
Subject(s) - folfirinox , medicine , surgical oncology , hazard ratio , pancreatic cancer , induction chemotherapy , oncology , multivariate analysis , chemotherapy , cancer , surgery , oxaliplatin , confidence interval , colorectal cancer
Effective chemotherapy (CTx) protocols as induction treatment provide increasing opportunities for surgical resection of locally advanced pancreatic cancer (LAPC). Although improved survival after resection of LAPC with CTx has been reported for selected patients, reliable recommendations on the indication for conversion surgery after induction treatment are currently lacking. We investigated the factors predictive of prognosis in resected LAPC after FOLFIRINOX.