In the article “ACTH versus vigabatrin in infantile spasms: A retrospective study” by Cossette et al. (1999;52:1691–1694), the statistical method used to evaluate the differences between both groups should have been the Fisher exact test rather than the chi-square test (owing to the small number of individuals in certain groups). This renders the differences in relapse rates not statistically significant, with p values at 3, 6, and 12 months of 0.11, 0.10, and 0.17, respectively. The …