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It has been shown that sick newborn infants tolerate excessive handling very poorly especially in very low birthweight infants. We chose to monitor TcPO2 in 9 term & 7 preterm infants during spinal tap procedure. The indications of CSF tap in 9 term infants were sepsis & meningitis, none of them had obvious lung disease. 7 preterm infants were tapped because of suspicion of sepsis, meningitis or intracranial hemorrhage, all had RDS. All showed TcPO2 reduction during positioning & tapping which took av. of 10 min.

1447 HARMFUL EFFECT OF LUMBAR PUNCTURE IN NEWBORN INFANTS