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We summarise here the information to be provided to women and referring physicians about percutaneous breast biopsy and lesion localisation under imaging guidance. After explaining why a preoperative diagnosis with a percutaneous biopsy is preferred to surgical biopsy, we illustrate the criteria used by radiologists for choosing the most appropriate combination of device type for sampling and imaging technique for guidance. Then, we describe the commonly used devices, from  fine - needle sampling  to tissue biopsy with larger needles, namely  core needle biopsy  and  vacuum - assisted biopsy , and how  mammography ,  digital breast tomosynthesis ,  ultrasound , or  magnetic resonance imaging  work for targeting the lesion for sampling or localisation. The differences among the techniques available for localisation ( carbon marking ,  metallic wire ,  radiotracer injection ,  radioactive seed ,  and magnetic seed localisation ) are illustrated. Type and rate of possible complications are described and the issue of concomitant antiplatelet or anticoagulant therapy is also addressed. The importance of  pathological - radiological correlation  is highlighted: when evaluating the results of any needle sampling, the radiologist must check the concordance between the cytology/pathology report of the sample and the radiological appearance of the biopsied lesion. We recommend that special attention is paid to a proper and tactful approach when communicating to the woman the need for tissue sampling as well as the possibility of cancer diagnosis, repeat tissue sampling, and or even surgery when tissue sampling shows a lesion with uncertain malignant potential (also referred to as “high-risk” or B3 lesions). Finally, seven frequently asked questions are answered.

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Image-guided breast biopsy and localisation: recommendations for information to women and referring physicians by the European Society of Breast Imaging