English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background  Zooprophylaxis is a technique in which blood-seeking vectors are diverted to non-host animals in order to lower blood-feeding rates on human hosts. The success of this technique depends on the host preference of the vector being targeted. The objective of this study was to evaluate the effect of  l -lactic acid (Abate) to divert malaria mosquito,  Anopheles gambiae  from feeding on human host.    Methods  A 14-month-old female goat was treated with Abate, a formulation incorporating  l -lactic acid into a slow-release matrix. This formulation was applied on the fur of the goat’s back and neck. The treated animal was then presented to  Anopheles gambiae  sensu stricto ( s.s .) as a prospective host in a semi-field environment (‘mosquito sphere’) together with either an untreated animal or a human. The number of mosquitoes caught to each host choice offered were compared.    Results  Goat treated with the  l -lactic acid formulation successfully attracted  An. gambiae  at higher rates (70.2%) than the untreated ones (29.8%). Furthermore,  An. gambiae s.s.  were attracted to a treated goat at an equivalent degree (47.3%) as to their preferred human host (52.7%), even when the preferred host was present in the same environment.    Conclusions  The findings indicate that human host-seeking mosquitoes can be diverted into feeding on non-preferred hosts despite the close proximity of their favoured host, hence reducing chances for the transmission of blood-borne parasites.

A zooprophylaxis strategy using l-lactic acid (Abate) to divert host-seeking malaria vectors from human host to treated non-host animals