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Background  Cats can be infested with several ectoparasite species, especially  Ctenocephalides felis  and  Otodectes cynotis . The aim of this study was to evaluate the efficacy of a single topical application of fluralaner against  C. felis  and  O. cynotis  natural infestation in stray (study 1) and owned (study 2) cats in central and southern Italy.    Results  The number of live fleas found on each cat on Day 0 ranged from 1 to more than 30 (arithmetic mean live flea count = 11.9 in study 1; 14.6 in study 2) while no live fleas were found on days 7 and 84 post topical application of fluralaner. The number of live mites found on each cat on Day 0 ranged from 1 to 42 (arithmetic mean live mite count = 6.4 in study 1; 8.9 in study 2) while no live mites were found on days 7 and 84 post topical application of fluralaner.    Conclusions  Topical fluralaner completely eliminated fleas and ear mites from infested cats and was 100% effective against both parasites up to 84 days after treatment.

Efficacy of fluralaner spot-on solution for the treatment of Ctenocephalides felis and Otodectes cynotis mixed infestation in naturally infested cats