English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background  Few studies have investigated the relationship between carotid-femoral pulse wave velocity (cfPWV) and serum alanine aminotransferase (ALT) normal-range levels across the world. The current analysis was designed to explore the relationship of serum ALT normal-range levels to cfPWV and metabolic syndrome (Mets) in non-drinkers and drinkers in a Chinese community-dwelling population.    Methods  There were 2202 participants with serum ALT levels within normal range enrolled for the current analysis.    Results  Median (range) age of participants was 53 (18–96) years, 51.5% were males, and 31.2% were drinkers. Prevalence of Mets was 29.4%. Median (range) of cfPWV was 10.1 (2.4-32.7) m/s. Hazard ratios for prevalence of Mets, central obesity and high triglyceride significantly increased with elevated levels of serum ALT in both non-drinkers and drinkers ( p  &lt; 0.05 for all). Hazard ratios for prevalence of cfPWV &gt; 10 m/s, high blood pressure and high blood glucose significantly increased with elevated levels of serum ALT in non-drinkers ( p  &lt; 0.05 for all), but not in drinkers ( p  ≥ 0.05 for all).    Conclusions  In a Chinese community-dwelling population, prevalence of Mets and its components (including central obesity and high TG) increased with an elevation in serum ALT levels within normal range in both non-drinkers and drinkers, while cfPWV and other components of Mets, such as high blood pressure and glucose, increased with an elevation in serum ALT levels in non-drinkers, but not in drinkers.

bmc gastroenterology

The relationship of serum alanine aminotransferase normal-range levels to arterial stiffness and metabolic syndrome in non-drinkers and drinkers: a Chinese community-based analysis