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Background  Forced expiratory volume in one second (FEV 1 ) is used to diagnose and establish a prognosis in chronic obstructive pulmonary disease (COPD). Using multi-dimensional scores improves this predictive capacity.Two instruments, the BODE-index ( B ody mass index,  O bstruction,  D yspnea,  E xercise capacity) and the HADO-score ( H ealth,  A ctivity,  D yspnea,  O bstruction), were compared in the prediction of mortality among COPD patients.    Methods  This is a prospective longitudinal study. During one year (2003 to 2004), 543 consecutively COPD patients were recruited in five outpatient clinics and followed for three years. The endpoints were all-causes and respiratory mortality.    Results  In the multivariate analysis of patients with FEV 1  < 50%, no significant differences were observed in all-cause or respiratory mortality across HADO categories, while significant differences were observed between patients with a lower BODE (less severe disease) and those with a higher BODE (greater severity). Among patients with FEV 1  ≥ 50%, statistically significant differences were observed across HADO categories for all-cause and respiratory mortality, while differences were observed across BODE categories only in all-cause mortality.    Conclusions  HADO-score and BODE-index were good predictors of all-cause and respiratory mortality in the entire cohort. In patients with severe COPD (FEV 1  < 50%) the BODE index was a better predictor of mortality whereas in patients with mild or moderate COPD (FEV 1  ≥ 50%), the HADO-score was as good a predictor of respiratory mortality as the BODE-index. These differences suggest that the HADO-score and BODE-index could be used for different patient populations and at different healthcare levels, but can be used complementarily.

BODE-Index vs HADO-Score in Chronic Obstructive Pulmonary Disease: Which one to use in general practice?