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Pediatric chronic nonbacterial osteomyelitis (CNO) is a sterile inflammatory bone disorder of presumed autoimmune or autoinflammatory etiology. Sometimes CNO associated with other rheumatologic conditions, such spondyloarthritis, sacroileitis, IBD, pyoderma gangrenosum and psoriasis as well as a part of distinct autoinflammatory disease (AID), such as DIRA syndrome.

P03-006 - Pamidronate rapidly decreases CRP and TNFΑ in CNO