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Background Non-randomized studies have reported a prognostic advantage with percutaneous coronary intervention (PCI) in the treatment of chronic total occlusions (CTO). However failure to cross and successfully open a CTO confers a worse clinical outcome. Quantitative assessment of global left ventricular (LV) function in those with failure to open a CTO has not demonstrated deleterious alterations in cardiac function/remodeling. We hypothesized that more sensitive techniques that assess regional wall motion, such as strain imaging, may identify segments where cardiac function is adversely affected in those with failure to open the CTO. Methods

Failure to successfully open a chronic total coronary occlusion is associated with preserved global, but impaired regional myocardial function