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Background Symptoms of heart failure are a late but strong predictor of adverse outcome in atrial switch patients. Long term adaptation of the systemic right ventricle and left ventricle is a complex process with modifications in ventricular volumes, mass, geometry and function, combined with fibrosis. These remodeling parameters need to be further investigated to guide difficult management strategies regarding medical, interventional and resynchronization therapy. In particular, we hypothesized that an adverse remodeling pattern based on geometric and functional parameters of both ventricles in atrial switch patients could be determined by CMR and differentiate symptomatic from asymptomatic patients. The subsequent study was to compare the remodeling parameters in patients to a normal population.

journal of cardiovascular magnetic resonance

1070 Adverse systemic right ventricular remodeling and ventricular interdependence leading to symptoms in atrial switch patients with transposition of the great vessels can be detected by biventricular geometry, function and mass assessment in CMR